Acral Persistent Papular Mucinosis: is it an under-diagnosed disease?

Acral persistent papular mucinosis and lichen myxedematosus.

Acral Persistent Papular Mucinosis with Partial Response to Tacrolimus Ointment

Received June 11, 2015, Revised July 21, 2015, Accepted for publication August 10, 2015 Corresponding author: Dong-Youn Lee, Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea. Tel: 82-2-3410-3543, Fax: 82-2-3410-3869, E-mail: [email protected] This is an Open Access article distributed under the terms of the C...

Acral papular mucinosis: a new case of this rare entity*

Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus. It consists of small papules localized exclusively on the back of the hands, wrists and extensor aspects of distal forearms with no other clinical or laboratory manifestations. The lesions tend to persist and may increase slowly in number. Histologically, hematoxylin-eosin and Alcian blue staining dem...

Acral papular eruption.

On examination, there were multiple skin colored to erythematous and edematous papules of about 1 to 5 mm size [Figure 1]. Many of the lesions, located over the extensor aspects of hands [Figure 2], forearms, elbows and upper arms were topped with tiny crusts and scales whereas others showed a central dusky hue. Examination of the conjunctiva revealed mild icterus. Bilateral axillary, epitrochl...

[Papular mucinosis associated with hypothyroidism].

Papular mucinosis or lichen myxedematosus is an idiopathic disorder characterized by papules, nodules or plaques caused by mucin deposition in the dermis, in the absence of thyroid disease. The present report describes an atypical case with exuberant lesions in the form of plaques, associated with subclinical hypothyroidism. In cutaneous mucinosis, there is an abnormal quantity of mucin in the ...